Adult giant hemangioma of the larynx: A case report

Truong Khuong Nguyen, Nhat Vinh Le

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Abstract

Background: Hemangiomas are relatively rare, slow-growing benign tumors that can cause necrosis, ulceration and infection leading to airway obstruction or hemorrhage. Treatment approaches have not yet been agreed, in­cluding active monitoring, corticosteroids, injectable sclerotherapy, laser therapy, and surgical resection.


Case report: A 40-year-old woman with a 6-month history of persistent throat clearing and foreign body sensa­tion. In the last 2 months, the patient's shortness of breath gradually increased. The patient bought himself medi­cine to treat indigestion and stomach pain at the pharmacy, when his breathing got worse, he went to the doctor, laryngoscopy and CT scan showed a large, irregular, lobulated tumor, covered by a dark purple mucosa occupying the entire glottis, the vocal cords are not visible. Patients with a history of prosthetic mitral valve replacement are on anticoagulation. The patient was tracheostomy, then general anesthesia through the tracheal cannula. Hemangiomas adjacent to the epiglottis were reduced in size by bipolar electrocautery. The base of the tumor was removed with an ultrasound scalpel. After 2 months of follow-up, there was no sign of recurrence.


Conclusion: The treatment of oropharyngeal hemangiomas still faces many difficulties. It is important to select treatments considering the characteristics of the treatment method and the anatomical and functional relation­ship between the hemangioma and surrounding structures. Bipolar electrocautery combined with translaryngo- scopic ultrasound knife resection may be an effective treatment for oropharyngeal hemangiomas.

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References

1. Zheng JW, Zhou Q, Yang XJ, et al. Treatment guideline for hemangiomas and vascular mal¬formations of the head and neck. Head Neck. 2010; 32(8): 1088-98
2. Wang WH, Tsai KY. Transoral robotic resection of an adult laryngeal haemangioma and review of the literature. / Larỵngol Otol. 2015; 129(6): 614-18
3. Valls-Mateus M, Roman LS, Macho J, et al. Transoral ultrasonic surgery of pharyngolaryn¬geal giant hemangioma after ethylene-vinyl alco¬hol copolymer (Onyx) embolization. Head Neck. 2017; 39(6): 1239-42
4. Kawakami M, Hayashi I, Yoshimura K, et al. Adult giant hemangioma of thelarynx: A case re¬port. Auris Nasus Larynx. 2006; 33(4): 479-82
5. Kishimoto Y, Hirano S, Kato N, et al. Endoscop¬ic KTP laser photocoagulation therapy for pharyn-golaryngeal venous malformations in adults. Ann Otol Rhinol Laryngol. 2008; 117(12): 881-85
6. Wang X, Zhao X, Zhu w. Resection of a laryn¬geal hemangioma in an adult using an ultrasonic scalpel: A case report. Oncol Lett. 2015; 9(6): 2477-80
7. Huang CM, Lee KW, Huang CJ. Radiation ther¬apy for life-threatening huge laryngeal hemangio¬ma involving pharynx and parapharyngeal space. Head Neck. 2013; 35(4): E98-101
8. Lucioni M, Marioni G, Della Libera D, et al. Adult laryngeal hemangioma C02 laser excision. A single institution 3-year experience (Vittorio Vene- to 2001-2003). Acta Otolaryngol. 2006; 126(6): 621- 26
9. Bannon R, Gohil R, Manickavasagam J. Lapa¬roscopic instrument use in laryngeal surgery: Tran¬-soral resection of a supraglottic haemangioma. J Laryngol Otol. 2017; 131(9): 823-26
10. Aluffi Valletti P, Toso A, Gorris C, et al. Adult la¬ryngeal ossified hemangioma: Difficulties in differ-ential diagnosis. J Craniofac Surg. 2018; 29(8): e730- 32
11. Xu S, Yu Y, ElHakim H, et al. The therapeutic effect of the combination of intratumor injection of bleomycin and electroresection/electrocautery on the hemangiomas in hypopharynx and larynx through suspension laryngoscopy. Ann Otol Rhinol Laryngol. 2019; 128(6): 575-80
12. Chen WL, Yang ZH, Bai ZB, et al. A pilot study on combination compartmentalisation and sclero-therapy for the treatment of massive venous mal¬formations of the face and neck. J Plast Reconstr AesthetSurg. 2008; 61(12): 1486-92
13. Martins RH, Lima Neto AC, Semenzate G, et al. Laryngeal hemangioma. Braz J Otorhinolaryngol. 2006; 72(4): 574
14. Enjolras O, Brevière GM, Roger G, et al. [Vin¬cristine treatment for functionand life-threatening infantile hemangioma]. Arch Pediatr. 2004; 11 (2): 99-107[in French]
15. Kamijo A, Hatsushika K, Kanemaru S, et al. Five adult laryngeal venous malformation cases treated effectively with sclerotherapy. Laryngoscope. 2013;123(ll): 2766-69
16. Orlando JL, Caldas JG, Campos HG, et al. Eth¬anol sclerotherapy of head and neck venous malfor¬mations. Einstein (Sao Paulo), 2014; 12(2): 181-86
17. O’Neill JV, Snyder GG 3rd, Toomey JM. Cryo¬surgery of supraglottic cavernous hemangioma. Arch Otolaryngol. 1976; 102(1): 55
18. Batta K, Goodyear HM, Moss C, et al. Ran¬domised controlled study of early pulsed dye la¬ser treatment of uncomplicated childhood hae- mangiomas: Results of a 1-year analysis. Lancet. 2002; 360 (9332): 521-27.
19. Zeitels SM, Burns JA. Laser applications in laryngology: Past, present, and future. Otolaryngol Clin North Am. 2006; 39(l): 159-72.
20. Park YM, Lim JY, Kang MS, et al. Treatment outcomes of angiolytic laser-assisted glottoplasty in patients with sulcus vocalis. Ann Otol Rhinol Laryn¬gol. 2019; 128(5): 377-83.