Tổng quan luận điểm hiệu quả tiêm steroid tại chỗ trong điều trị bệnh lành tính dây thanh

Abstract

Objective: Evaluate the effect of local steroid injection to treat benign vocal cord diseases. Methods: the analytic framework was based on a scoping review methodology. The databases Pubmed, Google Scholar, Sciencedirect, Cochrane were searched to identify relevant studies. Results: the benign vocal fold diseases include vocal nodules, polyp, Reinke's edema, mucous retention cyst, vocal process granuloma and vocal fold scars. After 1-3 months of simple local steroid injection, the improvement rate: vocal nodules 75 - 100%; Polyp 70 - 100%; Reinke’s edema 95 - 97%; Mucous retension cyst 76 - 84%, vocal process granuloma 75- 100%, vocal fold scars 70 - 76%. After 1- 3 months of local steroid injection combined with voice therapy or laryngeal microsurgery, the improvement rate: vocal nodules 96 - 100%; Polyp 85 - 100%; Reinke’s edema 100%; Mucous retension cyst 70- 100%, vocal fold scars 80%. Conclusion: Simple local steroid injections for treatment of benign vocal fold disorders had high effectiveness (>70%). Local steroid injection combined with voice training or laryngeal microsurgery increased the rate of treatment effectiveness. Among benign vocal cord diseases: vocal nodules, polyp and Reinke's edema respond better to topical steroid injection than mucous retension cysts and vocal cord scars.