CLINICAL AND PARACLINICAL CHARACTERISTICS AND HISTOPATHOLOGICAL CORRELATION OF SINONASA HEMANGIOMAS

Thanh Thao Pham1, Trung Dung Dao1,2, Ba Hung Do1,3, Thi Thu Hang Tran1,3,
1 Hanoi Medical University
2 Bach Mai Hospital
3 National Otorhinolaryngology Hospital of Vietnam

Main Article Content

Abstract

Objective: To describe the clinical and computed tomography features of sinonasal hemangiomas and correlate them with histopathological subtypes. Methods: A retrospective descriptive case series of 62 patients treated at the National Hospital of Otorhinolaryngology from January 2023 to March 2026. Results: Mean age was 43.4 ± 19.0 years; male/female = 1.3/1; capillary/cavernous hemangioma = 1/1. Epistaxis occurred in 61.3% and nasal obstruction in 51.6%. Endoscopically, tumors were pink (61.3%), smooth-surfaced (74.2%) and bled easily (58.1%). On CT, 88.7% enhanced after contrast, 16.1% showed bone erosion, and median size was 21.5 mm (9–37.5). Attachment sites were the paranasal sinuses (35.4%), turbinates (32.3%) and septum (16.1%). The two subtypes did not differ in age, sex, symptoms or surface morphology (p>0.05), but differed significantly in color (p<0.01), attachment site (p<0.001), bone erosion and tumor size (p<0.05). Conclusions: Sinonasal hemangiomas occur mainly in middle-aged adults, presenting with epistaxis and nasal obstruction. Capillary hemangiomas arise mainly within the nasal cavity, whereas cavernous hemangiomas arise from the sinuses and are larger with more bone erosion.

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References

1. Nagameenalochini M. A Review on the Histological Types of Hemangioma | Journal of Pharmaceutical Research International. Accessed May 19, 2026. https://journaljpri.com/index.php/JPRI/article/view/4802
2. WHO Classification of Tumours Editorial Board. Head and Neck Tumours. 5th ed. International Agency for Research on Cancer; 2022.WHO Classification of Tumours; vol 9
3. Kim JS, Kwon SH. Sinonasal Hemangioma: Diagnosis, Treatment, and Follow-Up of 37 Patients at a Single Center. J Oral Maxillofac Surg Off J Am Assoc Oral Maxillofac Surg. 2017;75(8):1775-1783. doi:10.1016/j.joms.2016.12.044
4. Takaishi S, Asaka D, Nakayama T, et al. Features of sinonasal hemangioma: A retrospective study of 31 cases. Auris Nasus Larynx. 2017;44(6):719-723. doi:10.1016/j.anl.2017.01.012
5. Iwata N, Hattori K, Nakagawa T, Tsujimura T. Hemangioma of the nasal cavity: a clinicopathologic study. Auris Nasus Larynx. 2002;29(4):335-339. doi:10.1016/s0385-8146(02)00028-7
6. Lee DG, Lee SK, Chang HW, et al. CT Features of Lobular Capillary Hemangioma of the Nasal Cavity. AJNR Am J Neuroradiol. 2010;31(4):749-754. doi:10.3174/ajnr.A1908
7. Kim JH, Park SW, Kim SC, et al. Computed Tomography and Magnetic Resonance Imaging Findings of Nasal Cavity Hemangiomas According to Histological Type. Korean J Radiol. 2015;16(3):566-574. doi:10.3348/kjr.2015.16.3.566
8. Tovmasyan AS, Klimenko KE, Zelikovich EI, et al. [Sinonasal hemangiomas: principles of diagnosis and treatment. Literature review]. Vestn Otorinolaringol. 2024;89(4):54-59. doi:10.17116/otorino20248904154
9. The Nasal Hemangioma - PMC. Accessed June 4, 2026. https://pmc.ncbi.nlm.nih.gov/articles/PMC6848360/
10. Al-Ani RM, Bargas OM. Demographic and clinical criteria of intranasal lobular capillary hemangioma: as retrospective multicentric audit. Egypt J Otolaryngol. 2022;38(1):1-6. doi:10.1186/s43163-022-00306-x
11. Smith SC, Patel RM, Lucas DR, McHugh JB. Sinonasal Lobular Capillary Hemangioma: A Clinicopathologic Study of 34 Cases Characterizing Potential for Local Recurrence. Head Neck Pathol. 2012;7(2):129-134. doi:10.1007/s12105-012-0409-9
12. Puxeddu R, Berlucchi M, Ledda GP, Parodo G, Farina D, Nicolai P. Lobular capillary hemangioma of the nasal cavity: A retrospective study on 40 patients. Am J Rhinol. 2006;20(4):480-484. doi:10.2500/ajr.2006.20.2878
13. Jammal H, Barakat F, Hadi U. Maxillary sinus cavernous hemangioma: a rare entity. Acta Otolaryngol (Stockh). 2004;124(3):331-333. doi:10.1080/00016480310015687
14. Vargas MC, Castillo M. Sinonasal cavernous haemangioma: a case report. Dentomaxillofacial Radiol. 2012;41(4):340-341. doi:10.1259/dmfr/89601569
15. Lim HR, Lee DH, Lim SC. Clinical Difference Between Capillary and Cavernous Hemangiomas of Nasal Cavity. J Craniofac Surg. 2021;32(3):1042-1044. doi:10.1097/SCS.0000000000007250