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DOI: 10.60137/tmhvn.v70i72.314
Issue
Vol. 70 No. 72 (2025)
Section
Articles
How to Cite
Nguyen, H. Y., Dao, D. T., & Phung, T. H. COMPARISON OF CLINICAL, COMPUTED TOMATOGRAPHY AND HISTOPATHOLOGY FEATURES OF PATIENTS WITH EARLY STAGE LARYNGEAL CANCER. Vietnam Journal of Otorhinolaryngology - Head and Neck Surgery, 70(72). https://doi.org/10.60137/tmhvn.v70i72.314

COMPARISON OF CLINICAL, COMPUTED TOMATOGRAPHY AND HISTOPATHOLOGY FEATURES OF PATIENTS WITH EARLY STAGE LARYNGEAL CANCER

Hai Yen Nguyen1, Dinh Thi Dao2, Thi Hoa Phung3,
1 Bệnh viện Đa khoa tỉnh Phú Thọ
2 Bệnh viện Tai Mũi Họng Trung Ương
3 Đại học Y Dược - Đại học Quốc gia Hà Nội

Main Article Content

Abstract


Objective: To describe the clinical, computed tomography and histopathological features of patients with early-stage laryngeal cancer.


Methods: A retrospective and prospective cross-sectional study of 41 patients diagnosed with early-stage laryngeal cancer at the Department of Oncology - National ENT Hospital from September 2024 to October 2025.


Results: Mean age was 61.61 ± 9.89 years, 100% were male. Age group > 60 years accounted for 51.2%, 51-60 years 36.6%, 41-50 years 12.2%, no patients ≤ 40 years. Risk factors: smoking (85.4%), alcohol (70.7%), both alcohol and tobacco (68.3%). Reason for admission: 100% hoarseness. Clinical symptoms: hoarseness (100%), shortness of breath (39.0%), cough (2.4%), swallowing disorders (2.4%). Vocal cord mobility: 100% normal. Tumor origin: unilateral vocal cord (97.6%), bilateral vocal cords (2.4%). T staging by endoscopy: T1 (80.5%), T2 (19.5%). CT findings: contrast enhancement (92.7%), 100% without thyroid cartilage destruction. Histopathology: 100% squamous cell carcinoma with grade I (34.1%), grade II (64.5%), grade III (2.4%). Clinical-CT correlation: concordance for unilateral vocal cord lesion was 73.2%, T1 staging 68.3%, T2 19.5%.


Conclusion: Early-stage laryngeal cancer occurs exclusively in males, middle-aged and elderly. Tobacco and alcohol are the leading risk factors. Hoarseness is the main symptom. Squamous cell carcinoma is the only histopathological type. There is relative agreement between clinical and CT findings in disease staging.


Keywords

laryngeal cancer, early stage, computed tomography, histopathology

Article Details

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