BACTERIAL PATHOGENS, ANTIBIOTIC RESISTANCE, AND TREATMENT OUTCOMES IN PEDIATRIC ACUTE SUPPURATIVE OTITIS MEDIA AT NGHE AN OBSTETRICS AND PEDIATRICS HOSPITAL
Main Article Content
Abstract
Objective: To describe the bacterial etiology, antibiotic susceptibility patterns, and treatment outcomes of acute suppurative otitis media in children at Nghe An Obstetrics and Pediatrics Hospital in 2025. Subjects and Methods: A descriptive case series study. Results: Children under 6 years of age accounted for the highest proportion (80.8%), with a male-to-female ratio of 1.17:1. The most common causative pathogen was Staphylococcus aureus (32.7%), followed by Haemophilus influenzae (30.8%), Pseudomonas aeruginosa (17.3%), and Streptococcus pneumoniae (9.6%). Regarding antibiotic susceptibility: S. pneumoniae remained sensitive to vancomycin and quinolones but showed high resistance to β-lactams. H. influenzae remained highly susceptible to quinolones but was highly resistant to cephalosporins. S. aureus was resistant to most β-lactams and oxacillin, yet sensitive to vancomycin and linezolid. P. aeruginosa remained sensitive to several antibiotics. Treatment outcomes showed that 82.7% of patients were cured, 17.3% improved, and none worsened. The average treatment duration was 7.8 ± 2.2 days (ranging from 3 to 13 days). Reported complications included diffuse otitis externa (25.0%), mastoiditis (7.7%), and hearing loss (1.9%). Conclusion: The most common bacterial pathogens causing acute otitis media were S. aureus, H. influenzae, P. aeruginosa, and S. pneumoniae. High resistance was observed to β-lactam (penicillin and cephalosporin) and macrolide antibiotics, while quinolones and vancomycin maintained good sensitivity. Treatment outcomes were generally favorable. The most frequent complication was diffuse otitis externa.
Keywords
Acute suppurative otitis media, children, antibiotic susceptibility, complications.
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References
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