RISK FACTORS OF OTITIS MEDIA WITH EFFUSION IN CHILDREN: A CASE-CONTROL STUDY

Thi Thu Dan Nguyen, Thanh Thai Le , Phuoc Minh Hoang

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Abstract

Background: Otitis media with effusion (OME) is a common disease, especially in children. Objective: To study demographic and clinical characteristics, tympanometry, and risk factors of OME in children. Materials and methods: In a case-control study, 35 OME pediatric patients and 35 healthy children whose parents responded to questionnaires designed to capture the history of diseases in the early life of participants, family history of allergy, family socioeconomic status, and home environmental factors. Results: In the univariate analysis, there were associations between OME and exposure to smoking at home [odd ratios (OR)=2.97; p=0.029], snoring (OR=3.63; p=0.019), history of acute otitis media (AOM) (OR=7.11; p=0.002), history of upper respiratory tract infections (URTIs) (OR=6.30; p<0.0001). However, only two of them had statistically significant correlations with OME in the multivariate logistic regression model: history of acute otitis media [OR=5.98; 95% confidence interval (CI), 1.25-28.54; p=0.025], history of URTI (OR=7.33; 95% CI, 2.04-26.39; p=0.002). Conclusion: OME is asymptomatic, especially in children. URTI and acute otitis media in early life are closely associated with OME.

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References

1. Rosenfeld R.M., Shin J.J., Schwartz S.R., Coggins R., et al (2016), "Clinical Practice Guideline: Otitis Media with Effusion (Update)", Otolaryngol Head Neck Surg, 154 (1 Suppl), pp. S1-s41.
2. Daly K.A., Hoffman H.J., Kvaerner K.J., Kvestad E., Casselbrant M.L., et al (2010), "Epidemiology, natural history, and risk factors: panel report from the Ninth International Research Conference on Otitis Media", Int J Pediatr Otorhinolaryngol, 74(3), pp. 231- 240.
3. Kiris M., Muderris T., Kara T., Bercin S., et al (2012), "Prevalence and risk factors of otitis media with effusion in school children in Eastern Anatolia", Int J Pediatr Otorhinolaryngol, 76 (7), pp. 1030-1035.
4. Nguyen T.N.A (2018), "Study on clinical and subclinical characteristics of otitis media with effusion on V.A inflammation in Otolaryngology Department of Thai Nguyen Central Hospital", Journal of Science and Technology, 188(12), pp. 113-119.
5. Lee J.Y., Kim S.H. (2018), "Risk factors for persistent otitis media with effusion in children: a case-control study", 35 (1), pp. 70-75.
6. Humaid A.H., Ashraf A.H., Masood K.A., Nuha A.H., et al (2014), "Prevalence and risk factors of Otitis Media with effusion in school children in Qassim Region of Saudi Arabia", Int J Health Sci (Qassim), 8 (4), pp. 325-334.
7. Gultekin E., Develioglu O.N., Yener M., Ozdemir I., et al (2010), "Prevalence and risk factors for persistent otitis media with effusion in primary school children in Istanbul, Turkey", Auris Nasus Larynx, 37 (2), pp. 145-149.
8. Martines F., Bentivegna D., Maira E., Sciacca V., et al (2011), "Risk factors for otitis media with effusion: case- control study in Sicilian schoolchildren", Int J Pediatr Otorhinolaryngol, 75 (6), pp. 754-759.
9. Quach T.C. (2011), " Situation and risk factors for otitis media with effusion in children under 12 years old in Tot Dong commune, Chung My district, Hanoi in 2011", Military Medical and Pharmaceutical Journal, number 9/2011, pp. 1-7.