INVESTIGATION OF SEVERE PROGNOSTIC FACTORS IN PATIENTS WITH DEEP NECK INFECTIONS AT CHO RAY HOSPITAL
Nội dung chính của bài viết
Tóm tắt
Background: Deep neck infection (DNI) is a severe otorhinolaryngological emergency with a high risk of rapid spread to critical structures, leading to complications and high mortality rates.
Objective: This study aims to identify severe prognostic factors in patients with DNI at Cho Ray Hospital (2023–2024).
Methods: A cross-sectional study was conducted with multivariate regression analysis to identify factors associated with severe progression and mortality. Data were collected from 151 patients medical records.
Results: Prognostic factors for ICU admission included dyspnea, NLR ≥20, necrotizing fasciitis, pneumonia, and mediastinitis. Prognostic factors for mortality included dyspnea, chest pain, NLR ≥20, necrotizing fasciitis, and septic shock.
Conclusion: Identifying severe prognostic factors can help clinicians recognize high-risk patients early for timely intervention, reducing complications and mortality.
Chi tiết bài viết
Tài liệu tham khảo
1. Almuqamam M, Gonzalez FJ, Sharma S, Kondamudi NP. Deep Neck Infections. StatPearls Publishing. Copyright © 2024, StatPearls Publishing LLC.; 2024.
2. McDowell RH, Hyser MJ. Neck Abscess. StatPearls Publishing. Copyright © 2024, StatPearls Publishing LLC.; 2024.
3. Priyamvada S, Motwani G. A Study on Deep Neck Space Infections. Indian J Otolaryngol Head Neck Surg. Oct 2019;71(Suppl 1):912-917. doi:10.1007/s12070-019-01583-4
4. Trương Minh T. Khảo sát các yếu tố tiên lượng nặng ở bệnh nhân nhiễm trùng cổ sâu tại Bệnh viện Chợ Rẫy từ 2019 đến 2022. Luận văn Bác sĩ nội trú. 2022.
5. Gunaratne DA, Tseros EA, Hasan Z, et al. Cervical necrotizing fasciitis: Systematic review and analysis of 1235 reported cases from the literature. Head Neck. Sep 2018;40(9):2094-2102. doi:10.1002/hed.25184
6. Ncogoza I, Munezero E, Mvukiyehe JP, Shaye D. Clinical presentation and factors leading to complications of deep neck space infections at CHUK. Rwanda Journal of Medicine and Health Sciences. 2021;4(1):8-19.
7. Suehara AB, Rodrigues AAN, Kavabata NK, et al. Predictive factors of lethality and complications of deep fascial space infections of the neck. Rev Col Bras Cir. Sep 4 2020;47:e20202524. doi:10.1590/0100-6991e-20202524
8. Barber BR, Dziegielewski PT, Biron VL, Ma A, Seikaly H. Factors associated with severe deep neck space infections: targeting multiple fronts. J Otolaryngol Head Neck Surg. 2014;43(1):35. doi:10.1186/s40463-014-0035-5
9. Huang TT, Liu TC, Chen PR, Tseng FY, Yeh TH, Chen YS. Deep neck infection: analysis of 185 cases. Head Neck. Oct 2004;26(10):854-60. doi:10.1002/hed.20014
10. Lê THA. Khảo sát vai trò của dinh dưỡng lâm sàng trong nhóm bệnh nhân nhiễm trùng cổ sâu tại Bệnh viện Chợ Rẫy từ năm 2020 đến năm 2021. Luận văn Bác sĩ nội trú. 2021.
11. Ho CY, Chan KC, Wang YC, Chin SC, Chen SL. Assessment of Factors Associated With Long-Term Hospitalization in Patients With a Deep Neck Infection. Ear Nose Throat J. Apr 3 2023:1455613231168478. doi:10.1177/01455613231168478
12. Huttunen R, Syrjänen J. Obesity and the risk and outcome of infection. Int J Obes (Lond). Mar 2013;37(3):333-40. doi:10.1038/ijo.2012.62
13. Park MJ, Kim JW, Kim Y, et al. Initial Nutritional Status and Clinical Outcomes in Patients with Deep Neck Infection. Clin Exp Otorhinolaryngol. Dec 2018;11(4):293-300. doi:10.21053/ceo.2018.00108
14. Đặng DL. Yếu tố nguy cơ gây kéo dài thời gian nằm viện của nhiễm trùng cổ sâu. Tạp chí Y học Việt Nam. 03/30 2023;524doi:10.51298/vmj.v524i2.4877
15. Liao TI, Ho CY, Chin SC, Wang YC, Chan KC, Chen SL. Sequential Impact of Diabetes Mellitus on Deep Neck Infections: Comparison of the Clinical Characteristics of Patients with and without Diabetes Mellitus. Healthcare (Basel). Jul 10 2024;12(14)doi:10.3390/healthcare12141383
16. Tao X, Hua H, Liu Y. A novel model for predicting mortality in the management of deep neck infections. Ear Nose Throat J. Nov 1 2022:1455613221133245. doi:10.1177/01455613221133245
17. Hidaka H, Yamaguchi T, Hasegawa J, et al. Clinical and bacteriological influence of diabetes mellitus on deep neck infection: Systematic review and meta-analysis. Head Neck. Oct 2015;37(10):1536-46. doi:10.1002/hed.23776
18. Boscolo-Rizzo P, Stellin M, Muzzi E, et al. Deep neck infections: a study of 365 cases highlighting recommendations for management and treatment. Eur Arch Otorhinolaryngol. Apr 2012;269(4):1241-9. doi:10.1007/s00405-011-1761-1
19. Mejzlik J, Celakovsky P, Tucek L, et al. Univariate and multivariate models for the prediction of life-threatening complications in 586 cases of deep neck space infections: retrospective multi-institutional study. J Laryngol Otol. Sep 2017;131(9):779-784. doi:10.1017/s0022215117001153
20. Grant SW, Hickey GL, Head SJ. Statistical primer: multivariable regression considerations and pitfalls. Eur J Cardiothorac Surg. Feb 1 2019;55(2):179-185. doi:10.1093/ejcts/ezy403
21. Staffieri C, Fasanaro E, Favaretto N, et al. Multivariate approach to investigating prognostic factors in deep neck infections. Eur Arch Otorhinolaryngol. Jul 2014;271(7):2061-7. doi:10.1007/s00405-014-2926-5
2. McDowell RH, Hyser MJ. Neck Abscess. StatPearls Publishing. Copyright © 2024, StatPearls Publishing LLC.; 2024.
3. Priyamvada S, Motwani G. A Study on Deep Neck Space Infections. Indian J Otolaryngol Head Neck Surg. Oct 2019;71(Suppl 1):912-917. doi:10.1007/s12070-019-01583-4
4. Trương Minh T. Khảo sát các yếu tố tiên lượng nặng ở bệnh nhân nhiễm trùng cổ sâu tại Bệnh viện Chợ Rẫy từ 2019 đến 2022. Luận văn Bác sĩ nội trú. 2022.
5. Gunaratne DA, Tseros EA, Hasan Z, et al. Cervical necrotizing fasciitis: Systematic review and analysis of 1235 reported cases from the literature. Head Neck. Sep 2018;40(9):2094-2102. doi:10.1002/hed.25184
6. Ncogoza I, Munezero E, Mvukiyehe JP, Shaye D. Clinical presentation and factors leading to complications of deep neck space infections at CHUK. Rwanda Journal of Medicine and Health Sciences. 2021;4(1):8-19.
7. Suehara AB, Rodrigues AAN, Kavabata NK, et al. Predictive factors of lethality and complications of deep fascial space infections of the neck. Rev Col Bras Cir. Sep 4 2020;47:e20202524. doi:10.1590/0100-6991e-20202524
8. Barber BR, Dziegielewski PT, Biron VL, Ma A, Seikaly H. Factors associated with severe deep neck space infections: targeting multiple fronts. J Otolaryngol Head Neck Surg. 2014;43(1):35. doi:10.1186/s40463-014-0035-5
9. Huang TT, Liu TC, Chen PR, Tseng FY, Yeh TH, Chen YS. Deep neck infection: analysis of 185 cases. Head Neck. Oct 2004;26(10):854-60. doi:10.1002/hed.20014
10. Lê THA. Khảo sát vai trò của dinh dưỡng lâm sàng trong nhóm bệnh nhân nhiễm trùng cổ sâu tại Bệnh viện Chợ Rẫy từ năm 2020 đến năm 2021. Luận văn Bác sĩ nội trú. 2021.
11. Ho CY, Chan KC, Wang YC, Chin SC, Chen SL. Assessment of Factors Associated With Long-Term Hospitalization in Patients With a Deep Neck Infection. Ear Nose Throat J. Apr 3 2023:1455613231168478. doi:10.1177/01455613231168478
12. Huttunen R, Syrjänen J. Obesity and the risk and outcome of infection. Int J Obes (Lond). Mar 2013;37(3):333-40. doi:10.1038/ijo.2012.62
13. Park MJ, Kim JW, Kim Y, et al. Initial Nutritional Status and Clinical Outcomes in Patients with Deep Neck Infection. Clin Exp Otorhinolaryngol. Dec 2018;11(4):293-300. doi:10.21053/ceo.2018.00108
14. Đặng DL. Yếu tố nguy cơ gây kéo dài thời gian nằm viện của nhiễm trùng cổ sâu. Tạp chí Y học Việt Nam. 03/30 2023;524doi:10.51298/vmj.v524i2.4877
15. Liao TI, Ho CY, Chin SC, Wang YC, Chan KC, Chen SL. Sequential Impact of Diabetes Mellitus on Deep Neck Infections: Comparison of the Clinical Characteristics of Patients with and without Diabetes Mellitus. Healthcare (Basel). Jul 10 2024;12(14)doi:10.3390/healthcare12141383
16. Tao X, Hua H, Liu Y. A novel model for predicting mortality in the management of deep neck infections. Ear Nose Throat J. Nov 1 2022:1455613221133245. doi:10.1177/01455613221133245
17. Hidaka H, Yamaguchi T, Hasegawa J, et al. Clinical and bacteriological influence of diabetes mellitus on deep neck infection: Systematic review and meta-analysis. Head Neck. Oct 2015;37(10):1536-46. doi:10.1002/hed.23776
18. Boscolo-Rizzo P, Stellin M, Muzzi E, et al. Deep neck infections: a study of 365 cases highlighting recommendations for management and treatment. Eur Arch Otorhinolaryngol. Apr 2012;269(4):1241-9. doi:10.1007/s00405-011-1761-1
19. Mejzlik J, Celakovsky P, Tucek L, et al. Univariate and multivariate models for the prediction of life-threatening complications in 586 cases of deep neck space infections: retrospective multi-institutional study. J Laryngol Otol. Sep 2017;131(9):779-784. doi:10.1017/s0022215117001153
20. Grant SW, Hickey GL, Head SJ. Statistical primer: multivariable regression considerations and pitfalls. Eur J Cardiothorac Surg. Feb 1 2019;55(2):179-185. doi:10.1093/ejcts/ezy403
21. Staffieri C, Fasanaro E, Favaretto N, et al. Multivariate approach to investigating prognostic factors in deep neck infections. Eur Arch Otorhinolaryngol. Jul 2014;271(7):2061-7. doi:10.1007/s00405-014-2926-5